Brisbane QLD, Australia, 6 January 2018 | AAP

Australian wildcard Alex de Minaur’s giant killing run has finally come to an end after going down 4-6 7-6 (7-5) 6-4 to unseeded American Ryan Harrison in the Brisbane International semi-finals.

The 18-year-old had become the youngest Australian to reach an ATP semi-final in 18 years and looked set for another stunning victory up 5-3 in the second set tiebreak at Pat Rafter Arena on Saturday.

But world No.47 Harrison – ranked 161 spots higher than the Sydney-born, Spain-based de Minaur – showed his experience to book a showdown against the winner of Saturday’s semi-final between third seed Nick Kyrgios and defending champion Grigor Dimitrov of Bulgaria.