Madrid, Madrid, Spain, 6 May 2015 | tennis.com.au

Nick Kyrgios and Sam Stosur will play feature matches at the Mutua Madrid Open when they face illustrious opposition on Manolo Santana court on Wednesday.

Kyrgios lines up against top seed and world No.2 Roger Federer in a blockbuster men’s second round clash, which you can catch live on ESPN.

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Kyrgios will face Federer on Madrid’s premier showcourt in the fourth match of the day, scheduled for approximately 5pm local time.

Stosur will follow Kyrgios onto Manolo Santana in the first of the night session’s matches, taking on Svetlana Kuznetsova.

The two women – both former Grand Slam champions and regular doubles partners – have met seven times previously, with Stosur leading the head-to-head 4-3 and having won their last three matches in straight sets.