New York, 8 September 2011 | AFP

Only 15 minutes of action took place on day 10 of the US Open on Wednesday before heavy rain brought a halt to proceedings, a day after torrential downpours wiped out the entire program.

All four women’s quarterfinals, two men’s quarters and the remaining four men’s fourth-round matches were all due to be played.

Action eventually started at 12.30 pm (2.30 am AEST) after a 90-minute delay.

Defending champion Rafael Nadal was trailing Gilles Muller 3-0 in the opening set, fourth seed Andy Murray was 2-1 down to America’s Donald Young, while former winner Andy Roddick was 3-1 up on fifth-seeded David Ferrer when the rain returned to send frustrated players and fans scurrying for cover.

In the other last-16 tie, John Isner faces Gilles Simon.

In the women’s quarterfinals, top seed Caroline Wozniacki, still searching for a first Grand Slam title, takes on Germany’s Andrea Petkovic, while three-time winner Serena Williams is up against Russian Anastasia Pavlyuchenkova.

Second seed Vera Zvonareva of Russia meets Australia’s Samantha Stosur, with unseeded German Angelique Kerber playing Italy’s Flavia Pennetta.

In the men’s quarters, world No.1 Novak Djokovic is up against fellow Serb Janko Tipsarevic and five-time champion Roger Federer clashes with Jo-Wilfried Tsonga.

Tuesday’s wipeout was the first time both the day and night sessions had been cancelled at the tournament since 2006.