Washington, USA, 10 January 2012 | AAP

Seven-time grand slam winner Venus Williams has withdrawn from the Australian Open as she struggles to return from the immune system disease Sjogren’s syndrome.

In a posting on her website, the US star said that she has been making progress and plans to return to WTA Tour play in February, when events begin in the United States.

“I regret to announce that I am withdrawing from the 2012 Australian Open,” Williams posted on her website.

“After several months of training and treatment, I am making steady progress to top competitive form.

“My diet and fitness regimen have allowed me to make great strides in terms of my health and I am very close to being ready to return to WTA competition. I have every intention to return to the circuit in February.”

Williams, whose ranking has slipped to 100th in the world, pulled out of last week’s WTA event in Auckland because of the illness, which saps her energy, causing fatigue and joint pains.

Williams, 31, is not the only member of her family in doubt for the first grand slam event of 2012.

Younger sister Serena, a 13-time grand slam singles champion, pulled out of last week’s event at Brisbane with a sprained ankle.

Serena Williams posted a Twitter message saying she was doing better, hinting she might be ready for the Australian Open that begins on Monday.